Mature epithelial cells
Squamous metaplasia, the process by which mature, non-squamous epithelium is replaced by stratified squamous epithelium, is a well-described phenomenon.
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Nov 30, Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming. Guo L(1), Karoubi G(1).
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Nov 30, Under clonogenic conditions, iPL cells expanded and functioned as a bronchiolar progenitor-like population to generate mature Club cells.
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Description:Because epithelial cells are known to synthesize IL, we investigated the effects of Chlamydia trachomatis infection of human epithelial cell lines on IL secretion. We confirmed that several human epithelial cell lines constitutively express pro-IL and that C. This was observed for several different serovars and biovars of C. Chlamydia-induced secretion of IL from epithelial cells was regulated at the posttranscriptional level and was dependent on the activation of caspase Activation of caspase-1 and increased secretion of mature IL was correlated with chlamydial, but not with host protein synthesis.